If you suspect major deficiency of antibodies in a person, to which of the following would you look for confirmatory evidence

Options

A. Fibrinogin in plasma
B. Serum albumins
C. Haemocytes
D. Serum globulins

Answer

To determine if there is a major deficiency of antibodies in a person, we need to look for a specific test that evaluates the presence of antibodies in the blood. Here’s a step-by-step solution to the question:

### Step-by-Step Solution:

1. **Understanding Antibodies**: Antibodies, also known as immunoglobulins, are protective proteins produced by the immune system. They play a crucial role in identifying and neutralizing pathogens like bacteria and viruses.

2. **Identifying the Tests**: The question provides several options for tests that could confirm the deficiency of antibodies. We need to evaluate each option to see which one is relevant to antibodies.

3. **Evaluating Option A - Fibrinogen in Plasma**: This test measures the function of fibrinogen, a protein essential for blood clotting. It does not provide information about antibodies. Therefore, this option is incorrect.

4. **Evaluating Option B - Serum Albumin**: Serum albumin is a protein that helps maintain blood volume and pressure and is involved in tissue repair. This test does not assess antibody levels, making this option incorrect as well.

5. **Evaluating Option C - Hemocyte**: Hemocytes are involved in wound repair and do not measure antibodies. This option is also incorrect.

6. **Evaluating Option D - Serum Globulin**: Serum globulin is a group of proteins in the blood that includes antibodies. This test evaluates the levels of globulins, which are crucial for confirming the presence or deficiency of antibodies in the blood. Therefore, this option is correct.

7. **Conclusion**: The most appropriate test to confirm a major deficiency of antibodies in a person is the serum globulin test.

### Final Answer:
The confirmatory evidence for a major deficiency of antibodies in a person would be obtained from the **serum globulin** test.

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