Which cell of immune system cause pore formation at the surface of the plasma membrane

Options

A. B-cell
B. Killer T-cell
C. Helper T-cell
D. Suppressor T-cell

Answer

To answer the question, "Which cell of the immune system causes pore formation at the surface of the plasma membrane?", we can follow these steps:

### Step-by-Step Solution:

1. **Understand the Immune System Cells**:
- The immune system consists of various types of cells, including B-cells, T-cells (which include helper T-cells, killer T-cells, and suppressor T-cells), and others.

2. **Identify the Function of Each Cell Type**:
- B-cells are primarily responsible for antibody production.
- Helper T-cells assist other immune cells in their functions.
- Suppressor T-cells help regulate and suppress immune responses.
- Killer T-cells (also known as cytotoxic T-cells) are responsible for directly killing infected or cancerous cells.

3. **Focus on Pore Formation**:
- Pore formation in the target cell's plasma membrane is a mechanism used by certain immune cells to induce cell death.
- The protein involved in this pore formation is called **perforin**.

4. **Identify the Cell Responsible for Pore Formation**:
- Among the options provided, killer T-cells are known to release perforin, which creates pores in the membranes of infected or malignant cells, leading to their destruction.

5. **Conclusion**:
- The correct answer to the question is **Killer T-cell**.

### Final Answer:
The cell of the immune system that causes pore formation at the surface of the plasma membrane is the **Killer T-cell**.

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