Go through the following Statements
(i) Cocaine interferes with the transport of neurotransmitter dopamine
(ii) Atropa belladona and Datura are used by criminals for stupefying, roadside robbery and kidnapping etc.
(iii) Nicotine stimulates adreal gland to release adrenaline and nor-adrenaline into blood circulation, both of which raise blood pressure and increase heart rate.
(iv) Pethidine, commonly called smack is chemically diacetylmorphine wihch is obtained by acetylation of morphine .
Which of these are correct?

Options

A. (i) & (iii)
B. (i), (iii) & (iv)
C. (i), (ii) & (iii)
D. All are correct

Explanation

To determine which statements are correct, let's analyze each one step by step:

**Step 1: Analyze Statement (i)**
- Statement: "Cocaine interferes with the transport of neurotransmitter dopamine."
- Explanation: Cocaine is known to block the reuptake of dopamine in the brain, leading to increased levels of dopamine in the synaptic cleft. This statement is correct.

**Step 2: Analyze Statement (ii)**
- Statement: "Atropa belladona and Datura are used by criminals for stupefying, roadside robbery and kidnapping etc."
- Explanation: Both Atropa belladonna and Datura are known for their psychoactive properties and can cause delirium and confusion. They have been used historically to incapacitate individuals, making this statement correct.

**Step 3: Analyze Statement (iii)**
- Statement: "Nicotine stimulates adrenal gland to release adrenaline and nor-adrenaline into blood circulation, both of which raise blood pressure and increase heart rate."
- Explanation: Nicotine indeed stimulates the adrenal glands to release adrenaline (epinephrine) and noradrenaline (norepinephrine), which leads to increased heart rate and blood pressure. This statement is also correct.

**Step 4: Analyze Statement (iv)**
- Statement: "Pethidine, commonly called smack, is chemically diacetylmorphine which is obtained by acetylation of morphine."
- Explanation: This statement is incorrect. Pethidine is a different synthetic opioid and is not referred to as "smack." "Smack" is a street name for heroin, which is diacetylmorphine. Therefore, this statement is incorrect.

**Conclusion:**
- The correct statements are (i), (ii), and (iii). Statement (iv) is incorrect.

**Final Answer:**
Statements (i), (ii), and (iii) are correct.

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