Asthma may be attributed to

Options

A. Allergic reaction of the mast cells in the lungs
B. Inflammation of the trachea
C. Accumulation of fluid in the lungs
D. Bacterial infection of the lungs

Answer

**Step-by-Step Solution:**

1. **Understanding Asthma**: Asthma is a chronic respiratory condition characterized by difficulty in breathing due to inflammation and narrowing of the airways.

2. **Identifying Causes**: The primary cause of asthma can often be attributed to an allergic reaction. This reaction occurs when the immune system overreacts to allergens.

3. **Role of Mast Cells**: Mast cells are immune cells found in the lungs that play a crucial role in allergic reactions. When an allergen is encountered, these cells release various substances, including histamines, which contribute to the symptoms of asthma.

4. **Symptoms of Asthma**: Common symptoms include:
- Constant coughing
- Wheezing (a whistling sound while breathing)
- Chest tightness
- Difficulty in breathing

5. **Mechanism of Action**: During an allergic reaction, mast cells secrete histamines, prostaglandins, and leukotrienes. These substances lead to bronchoconstriction (narrowing of the airways), increased mucus secretion, and mucosal edema (swelling of the airway lining).

6. **Evaluating Options**:
- **Allergic reaction of the mast cell in the lung**: Correct, as it is a primary cause of asthma.
- **Inflammation of the trachea**: Incorrect, as asthma primarily affects the bronchi and bronchioles.
- **Accumulation of fluid in the lungs**: Incorrect, this is not a typical symptom of asthma.
- **Bacterial infection of the lung**: Incorrect, asthma is not caused by bacterial infections.

7. **Conclusion**: The most accurate attribution for asthma is the allergic reaction of the mast cells in the lungs.

**Final Answer**: Asthma may be attributed to the allergic reaction of the mast cell in the lung.

---