Given below is a flow chart showing ovarian changes during menstrual cycle. Fill in the space with the hormonal factor / responsible for the events shown .

Explanation

To solve the question regarding the hormonal factors responsible for the ovarian changes during the menstrual cycle, we can break it down into three main steps based on the flowchart provided:

### Step-by-Step Solution:

1. **Identify the Hormones for Primary Follicle to Graafian Follicle Transition**:
- The first change in the flowchart is from the primary follicle to the Graafian follicle. This transition is stimulated by the **Follicle Stimulating Hormone (FSH)** and **Estrogen**. FSH promotes the growth of the ovarian follicles, and estrogen is produced by the follicles as they mature.
- **Answer for Option A**: FSH and Estrogen.

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