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Consider the following statements regadi...

Consider the following statements regading Na-K Pump
1. It utilizes ATP.
2. It acts on a resting neuron.
3. It invloves efflux of 3 `Na^(+)` per ATP.
4. It involves influx of 2 `K^(+)` per ATP.
5. Metabolic poisons stop the pump.

A

1 and 2

B

1, 2 and 5

C

3, 4 and 5

D

1, 2, 3, 4 and 5

Text Solution

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The correct Answer is:
To analyze the statements regarding the Sodium-Potassium (Na-K) Pump, we will evaluate each statement step by step. ### Step-by-Step Solution: 1. **Statement 1: It utilizes ATP.** - The Sodium-Potassium pump is an active transport mechanism that requires energy to function. This energy is derived from the hydrolysis of ATP (adenosine triphosphate). Therefore, this statement is **correct**. 2. **Statement 2: It acts on a resting neuron.** - The Sodium-Potassium pump is crucial for maintaining the resting membrane potential in neurons. It continuously works to keep the concentrations of sodium and potassium ions stable, even when the neuron is not actively firing. Thus, this statement is also **correct**. 3. **Statement 3: It involves efflux of 3 Na⁺ per ATP.** - The Sodium-Potassium pump transports three sodium ions (Na⁺) out of the cell for every ATP molecule hydrolyzed. This is a key feature of the pump's function. Therefore, this statement is **correct**. 4. **Statement 4: It involves influx of 2 K⁺ per ATP.** - In addition to the efflux of sodium ions, the pump also brings two potassium ions (K⁺) into the cell for each ATP molecule used. This is another essential aspect of the pump's operation. Hence, this statement is **correct**. 5. **Statement 5: Metabolic poisons stop the pump.** - Metabolic poisons, such as certain enzyme inhibitors, can interfere with ATP production or utilization, thereby halting the function of the Sodium-Potassium pump. This statement is also **correct**. ### Conclusion: All five statements regarding the Sodium-Potassium pump are correct. Therefore, the answer is that all statements (1, 2, 3, 4, and 5) are true. ### Final Answer: **Option D: All statements are correct.**
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