During synaptic transmission of nerve impulse, neurotransmitter (p) is released from synaptic vesicles by the action of ions (Q). Choose the correct P and Q

Options

A. P = acetylcholine, Q = `Ca^(++)`
B. P = acetylcholine, Q = `Na^(++)`
C. P = GABA, Q = `Na^(+)`
D. P = cholinesterase, Q = `Ca^(++)`

Answer

To solve the question regarding synaptic transmission of nerve impulses, we will follow these steps:

### Step-by-Step Solution:

1. **Understanding Synaptic Transmission**:
- Synaptic transmission is the process by which a nerve impulse is transmitted across a synapse from one neuron to another. This involves the release of neurotransmitters from the presynaptic neuron to the postsynaptic neuron.

2. **Identify the Components**:
- In the synapse, the presynaptic neuron contains synaptic vesicles filled with neurotransmitters. When an action potential reaches the axon terminal of the presynaptic neuron, it triggers the release of these neurotransmitters.

3. **Role of Calcium Ions**:
- The arrival of the action potential opens voltage-gated calcium channels in the presynaptic membrane. Calcium ions (Ca²⁺) then diffuse into the synaptic knob.

4. **Release of Neurotransmitters**:
- The influx of calcium ions causes the synaptic vesicles to fuse with the presynaptic membrane, leading to the release of neurotransmitters into the synaptic cleft.

5. **Identify the Neurotransmitter**:
- The most common neurotransmitter released at the neuromuscular junction is acetylcholine (ACh).

6. **Conclusion**:
- Based on the above steps, we can conclude that the neurotransmitter (P) is acetylcholine and the ions (Q) responsible for its release are calcium ions.

### Final Answer:
- **P is acetylcholine and Q is calcium ions** (Option A).

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