Choose the correct statement.

Options

A. Nociceptors respond to change in presure.
B. Meissner's corpuscles are thermoreceptors.
C. Photoreceptors in the human eye are depolarized during darkness and become hyperpolarized in response to the light stimulus
D. Receptors do not produces graded potentials.

Answer

To solve the question "Choose the correct statement," we need to analyze each of the provided statements one by one and determine which one is accurate.

### Step-by-Step Solution:

1. **Examine the First Statement:**
- **Statement:** "Receptors do not produce graded potential."
- **Analysis:** This statement is incorrect. Receptors, such as sensory receptors, do produce graded potentials. Graded potentials are changes in membrane potential that occur in response to stimuli and are essential for initiating action potentials in neurons.
- **Conclusion:** This statement is **wrong**.

2. **Examine the Second Statement:**
- **Statement:** "Nociceptor responds to change in pressure."
- **Analysis:** This statement is also incorrect. Nociceptors are specialized sensory receptors that respond primarily to pain stimuli, not to changes in pressure. They are activated by potentially damaging stimuli that can cause pain.
- **Conclusion:** This statement is **wrong**.

3. **Examine the Third Statement:**
- **Statement:** "Meissner corpuscles are thermoreceptors."
- **Analysis:** This statement is incorrect. Meissner corpuscles are mechanoreceptors that respond to light touch and pressure, not thermoreceptors. Thermoreceptors are specialized for detecting temperature changes.
- **Conclusion:** This statement is **wrong**.

4. **Examine the Fourth Statement:**
- **Statement:** "Photoreceptors in the human eye are depolarized during darkness and become hyperpolarized in response to light stimuli."
- **Analysis:** This statement is correct. In the dark, photoreceptors (rods and cones) are depolarized, allowing the release of neurotransmitters. When exposed to light, they hyperpolarize, which leads to a decrease in neurotransmitter release and the generation of action potentials in the associated bipolar cells.
- **Conclusion:** This statement is **right**.

### Final Answer:
The correct statement is **Option D**: "Photoreceptors in the human eye are depolarized during darkness and become hyperpolarized in response to light stimuli."

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