Enzymes involved in oxidative decarboxylation of pyruvic acid are found in

Options

A. cytoplasm
B. matrix of Mitochondrion
C. `F_0 - F_1` particles
D. oxysomes

Answer

**Step-by-Step Solution:**

1. **Understanding the Process**: The question asks about the enzymes involved in the oxidative decarboxylation of pyruvic acid. This process is crucial in cellular respiration, where pyruvic acid, produced from glycolysis, is further processed to enter the Krebs cycle.

2. **Identifying the Location of Glycolysis**: Glycolysis is the metabolic pathway that breaks down glucose into pyruvic acid. This process occurs in the cytoplasm of the cell. Therefore, enzymes involved in glycolysis are located in the cytoplasm.

3. **Movement of Pyruvic Acid**: After glycolysis, pyruvic acid is transported into the mitochondria. It does not remain in the cytoplasm; it needs to enter the mitochondria for further processing.

4. **Oxidative Decarboxylation**: Once inside the mitochondria, specifically in the matrix, pyruvic acid undergoes oxidative decarboxylation. This reaction converts pyruvic acid into acetyl-CoA, which is essential for the Krebs cycle.

5. **Enzymes in the Mitochondrial Matrix**: The key enzyme involved in the oxidative decarboxylation of pyruvic acid is pyruvate dehydrogenase. This enzyme is located in the matrix of the mitochondria, where the oxidative decarboxylation occurs.

6. **Conclusion**: Based on the above points, the enzymes involved in the oxidative decarboxylation of pyruvic acid are found in the **matrix of mitochondria**.

**Final Answer**: The correct answer is the matrix of mitochondria.

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