All enzymes of TCA cycle except succinic dehyd rogenase and cytochrome oxidase are found in

Options

A. cytosole and oxysomes
B. matrix of mitochondrion
C. inner membrane of mitochondrion
D. outer membrane of mitochondrion

Answer

### Step-by-Step Solution:

1. **Understanding the TCA Cycle**:
- The TCA cycle, also known as the Krebs cycle or citric acid cycle, is a crucial metabolic pathway that occurs in aerobic conditions. It involves a series of enzymatic reactions that are vital for energy production in cells.

2. **Identifying the Location of Enzymes**:
- Most enzymes of the TCA cycle are located in the matrix of mitochondria. This is where the majority of the reactions of the cycle take place.

3. **Exceptions to the General Rule**:
- The question specifies that two enzymes, succinic dehydrogenase and cytochrome oxidase, are exceptions. These enzymes do not reside in the mitochondrial matrix.

4. **Location of the Exception Enzymes**:
- Succinic dehydrogenase is tightly bound to the inner membrane of the mitochondria.
- Cytochrome oxidase is also found in the inner membrane of the mitochondria.

5. **Conclusion**:
- Therefore, all enzymes of the TCA cycle, except for succinic dehydrogenase and cytochrome oxidase, are found in the matrix of mitochondria. The two exceptions are found in the inner membrane of the mitochondria.

6. **Final Answer**:
- The correct answer to the question is that all enzymes of the TCA cycle, except succinic dehydrogenase and cytochrome oxidase, are found in the **inner membrane of mitochondria**.