Fructose-6-phosphate is changed to Fructose 1-6 biphosphate with the help of enzyme

Options

A. phosphoglycerate
B. enolase
C. phosphofructokinase
D. phosphatase

Answer

**Step-by-Step Solution:**

1. **Identify the Reaction**: The question asks about the conversion of fructose-6-phosphate to fructose-1,6-bisphosphate. This reaction is a key step in the glycolysis pathway.

2. **Recognize the Enzyme Involved**: The enzyme that catalyzes this specific reaction is known as phosphofructokinase (PFK). It plays a crucial role in regulating the glycolytic pathway.

3. **Understand the Process**: This conversion is a phosphorylation reaction, meaning that a phosphate group is added to fructose-6-phosphate to form fructose-1,6-bisphosphate. This process requires energy, which is provided by the hydrolysis of ATP (adenosine triphosphate).

4. **Eliminate Incorrect Options**:
- **Phosphoglycerate**: This is a metabolic intermediate in glycolysis and the Calvin cycle, but it is not the enzyme that catalyzes the reaction in question.
- **Enolase**: This enzyme catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate, which occurs later in glycolysis.
- **Phosphatase**: This enzyme is involved in removing phosphate groups from molecules, which is not relevant to the conversion of fructose-6-phosphate to fructose-1,6-bisphosphate.

5. **Conclusion**: The correct enzyme that facilitates the conversion of fructose-6-phosphate to fructose-1,6-bisphosphate is phosphofructokinase. Therefore, the answer is option C.

**Final Answer**: Phosphofructokinase (Option C).

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