Which one of the following mammalian cells is not capable of metabolising glucose to carbon-dioxide aerobically ?

Options

A. Liver cells
B. Red blood cells
C. White blood cells
D. Unstriated muscle cells

Answer

### Step-by-Step Solution:

1. **Understanding Aerobic Respiration**:
- Aerobic respiration is a process that occurs in the presence of oxygen and involves the breakdown of glucose to produce carbon dioxide, water, and energy (ATP). This process primarily takes place in the mitochondria of cells.

2. **Identifying the Options**:
- The options provided are:
- a) Liver cells
- b) Red blood cells (RBCs)
- c) White blood cells
- d) Unstriated muscle cells

3. **Analyzing Each Cell Type**:
- **Liver Cells**: These are nucleated cells that contain mitochondria and can metabolize glucose aerobically.
- **Red Blood Cells (RBCs)**: Mature RBCs are enucleated (lack a nucleus) and do not have mitochondria. Therefore, they cannot perform aerobic respiration and are dependent on anaerobic respiration for energy.
- **White Blood Cells**: These are nucleated cells that also contain mitochondria, allowing them to metabolize glucose aerobically.
- **Unstriated Muscle Cells**: These cells are nucleated and contain mitochondria, enabling them to perform aerobic respiration.

4. **Conclusion**:
- Among the given options, the cell type that cannot metabolize glucose to carbon dioxide aerobically is the **Red Blood Cells (RBCs)**, as they lack both a nucleus and mitochondria.

5. **Final Answer**:
- The correct answer is **b) Red Blood Cells (RBCs)**.