Which of the following is not a feature of the plasmids ?

Options

A. Circular structure
B. Transferable
C. Single-stranded
D. Independent replication

Answer

To determine which of the following is not a feature of plasmids, we need to analyze the given options based on the characteristics of plasmids.

### Step-by-Step Solution:

1. **Understanding Plasmids**:
- Plasmids are extra chromosomal DNA found in bacteria. They are distinct from the nuclear DNA and exist in the cytoplasm of bacterial cells.

2. **Identifying Characteristics of Plasmids**:
- **Circular Structure**: Plasmids are known to be circular in shape. This is a common feature of plasmids and is characteristic of prokaryotic DNA.
- **Transferable**: Plasmids can be transferred between bacterial cells, which is a key feature that allows for the spread of traits such as antibiotic resistance.
- **Independent Replication**: Plasmids can replicate independently of the bacterial chromosome, allowing them to be passed on during cell division.
- **Single-Stranded**: This is where we need to focus. Plasmids are actually double-stranded DNA, not single-stranded.

3. **Evaluating the Options**:
- **Option A: Circular Structure** - This is a feature of plasmids.
- **Option B: Transferable** - This is also a feature of plasmids.
- **Option C: Single-Stranded** - This is **not** a feature of plasmids, as they are double-stranded.
- **Option D: Independent Replication** - This is a feature of plasmids.

4. **Conclusion**:
- The correct answer is **Option C: Single-Stranded**, as this is not a feature of plasmids.

### Final Answer:
**C: Single-Stranded**

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