`O_(2)` dissociation curve is shifted to right in all except

Options

A. hype capenea
B. rise in temperature f
C. raised 2.3 dpg level
D. metabolic alkalosis

Answer

To solve the question regarding the factors that shift the O2 dissociation curve to the right, we will analyze each option provided.

### Step-by-Step Solution:

1. **Understanding the O2 Dissociation Curve**:
The O2 dissociation curve represents the relationship between the partial pressure of oxygen (pO2) and the saturation of hemoglobin with oxygen. A rightward shift indicates that hemoglobin releases oxygen more readily to the tissues.

2. **Factors that Cause Rightward Shift**:
- **Increased Temperature**: Higher temperatures decrease hemoglobin's affinity for oxygen, causing a rightward shift.
- **Increased CO2 Levels**: Higher levels of carbon dioxide (CO2) in the blood lead to a decrease in pH (Bohr effect), which also causes a rightward shift.
- **Increased 2,3-Diphosphoglycerate (2,3-DPG)**: Elevated levels of 2,3-DPG in red blood cells promote the release of oxygen from hemoglobin, resulting in a rightward shift.

3. **Analyzing the Options**:
- **Option A: Hypothermia**: This condition lowers body temperature, which would shift the curve to the left (increased affinity for oxygen).
- **Option B: Rise in Temperature**: This would shift the curve to the right.
- **Option C: Raised 2,3-DPG Level**: This would also shift the curve to the right.
- **Option D: Metabolic Alkalosis**: This condition increases blood pH, which would also shift the curve to the left (increased affinity for oxygen).

4. **Identifying the Exception**:
From the analysis, we see that hypothermia (Option A) is the only factor that does not cause a rightward shift in the O2 dissociation curve. Instead, it shifts the curve to the left.

### Conclusion:
The correct answer is **Option A: Hypothermia**.

---