Mature Graffian follicle is generally present in the ovary of a healthy human female around.

Options

A. 5-8 day of menstrual cycle
B. 11-17 day of menstrual cycle
C. 18-23 day of menstrual cycle
D. 24-28 day of menstrual cycle

Answer

To determine when the mature Graffian follicle is generally present in the ovary of a healthy human female, we can analyze the stages of the menstrual cycle. Here’s a step-by-step solution:

### Step-by-Step Solution:

1. **Understand the Menstrual Cycle**: The menstrual cycle typically lasts about 28 days and consists of several phases: menstruation, proliferative (follicular) phase, ovulation, and luteal phase.

2. **Identify the Phases**:
- **Menstruation Phase**: This occurs from day 1 to day 5, where the uterine lining sheds.
- **Proliferative Phase (Follicular Phase)**: This phase occurs from day 6 to day 13, during which the uterine lining thickens and follicles in the ovaries begin to develop.

3. **Ovulation**: Ovulation generally occurs on day 14 of the menstrual cycle. This is when the mature Graffian follicle releases an ovum (egg) into the fallopian tube.

4. **Formation of Corpus Luteum**: After ovulation, the remnants of the Graffian follicle transform into a structure called the corpus luteum, which plays a role in hormone production.

5. **Determine the Fertile Window**: The mature Graffian follicle is present around the time of ovulation. Considering the lifespan of sperm (approximately 24 hours) and the ovum (1 to 2 days), the fertile window extends about 3 days before and after ovulation.

6. **Conclusion**: Therefore, the mature Graffian follicle is generally present in the ovary of a healthy human female around days 11 to 17 of the menstrual cycle, with day 14 being the peak ovulation day.

### Final Answer:
The mature Graffian follicle is generally present in the ovary of a healthy human female around days 11 to 17 of the menstrual cycle, with ovulation occurring on day 14.

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