What is correct to say about the hormone action in humans ?

Options

A. Secretion of thymosins is stimulated with aging
B. In females, FSH first binds with specific receptors on ovarian cell membrane
C. FSH stimulates the secretion of estrogen and progesterone
D. Glucagon is secreted by beta-cells of islets of langerhans and stimulates glycogenolysis

Answer

To answer the question "What is correct to say about the hormone action in humans?", we can analyze the statements provided in the context of hormone action. Here’s a step-by-step breakdown of the analysis:

### Step 1: Analyze the Statement about Thymocines
- **Statement**: "Secretion of thymocines is stimulated with ageing."
- **Analysis**: Thymocines are hormones secreted by the thymus gland, which is responsible for the maturation of T lymphocytes (immune cells). However, the thymus gland tends to degenerate with age, leading to a decrease in thymosin production. Therefore, this statement is **incorrect**.

### Step 2: Analyze the Statement about FSH
- **Statement**: "In females, FSH first binds with specific receptors on ovarian cell membrane."
- **Analysis**: Follicle Stimulating Hormone (FSH) is crucial for the maturation of ovarian follicles. It binds to specific receptors on the ovarian cell membrane, which is necessary for its action. This statement is **correct**.

### Step 3: Analyze the Statement about FSH and Hormone Secretion
- **Statement**: "FSH stimulates the secretion of estrogen and progesterone."
- **Analysis**: While FSH does stimulate the maturation of follicles and the secretion of estrogen, it does not directly stimulate the secretion of progesterone. Progesterone is primarily secreted by the corpus luteum after ovulation. Therefore, this statement is **partially correct**, but misleading as it implies FSH directly controls progesterone secretion.

### Step 4: Analyze the Statement about Glucagon
- **Statement**: "Glucagon is secreted by the beta cells of islets of Langerhans and it stimulates glycogenolysis."
- **Analysis**: Glucagon is actually secreted by the alpha cells of the islets of Langerhans in the pancreas, not the beta cells (which secrete insulin). While glucagon does stimulate glycogenolysis (the breakdown of glycogen to glucose), the statement regarding its secretion is **incorrect**.

### Conclusion
After analyzing all the statements:
- The only **correct statement** regarding hormone action in humans is: **"In females, FSH first binds with specific receptors on ovarian cell membrane."**