Which layer of uterus undergoes cyclic changes during menstrual cycle

Options

A. Perimetrium
B. Myometrium
C. Endometrium
D. All the above

Explanation

**Step-by-Step Solution:**

1. **Understanding the Structure of the Uterus**: The uterus has three distinct layers: the outermost layer called the perimetrium, the middle layer known as the myometrium, and the innermost layer referred to as the endometrium.

2. **Identifying the Layers**:
- **Perimetrium**: This is the outer layer of the uterus.
- **Myometrium**: This is the middle muscular layer of the uterus.
- **Endometrium**: This is the innermost layer where implantation occurs and which is involved in the menstrual cycle.

3. **Cyclic Changes During the Menstrual Cycle**: The question specifically asks about the layer that undergoes cyclic changes during the menstrual cycle. The endometrium is the layer that thickens and sheds in response to hormonal changes.

4. **Hormonal Influence**: The cyclic changes in the endometrium are primarily influenced by hormones, particularly estrogen. Estrogen promotes the proliferation (thickening) of the endometrium in preparation for a potential pregnancy.

5. **Conclusion**: Based on the above points, the layer of the uterus that undergoes cyclic changes during the menstrual cycle is the **endometrium**.

**Final Answer**: The layer of the uterus that undergoes cyclic changes during the menstrual cycle is the **endometrium**.

---