Which of the following layers in an antral follicle is acellular?

Options

A. Granulosa
B. Theca interna
C. Stroma
D. Zona pellucida

Answer

To answer the question "Which of the following layers in an antral follicle is acellular?" we will analyze each option provided.

### Step-by-Step Solution:

1. **Understanding Antral Follicle**:
- An antral follicle is a tertiary follicle characterized by the presence of a fluid-filled cavity called the antrum.

2. **Identifying the Layers**:
- The layers of an antral follicle include:
- **Granulosa**: This layer is composed of cells that provide nutrition to the developing oocyte.
- **Theca Interna**: This is the inner layer of the theca, which is also composed of cells.
- **Stroma**: This refers to the connective tissue surrounding the follicle, which is also cellular.
- **Zona Pellucida**: This is a glycoprotein layer that surrounds the oocyte.

3. **Analyzing Each Option**:
- **Granulosa**: This layer is cellular, as it consists of granulosa cells.
- **Theca Interna**: This layer is also cellular, made up of theca cells.
- **Stroma**: The stroma is made up of connective tissue cells, hence it is cellular.
- **Zona Pellucida**: This layer is acellular, as it is primarily composed of glycoproteins secreted by the oocyte.

4. **Conclusion**:
- After analyzing all the options, it is clear that the **Zona Pellucida** is the acellular layer in the antral follicle.

### Final Answer:
The acellular layer in an antral follicle is the **Zona Pellucida**.

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