Identify the correct statement on 'inhibin'

Options

A. is produced by granulosa cells in ovary
B. Is produced by granulose cells in ovary and inhibits the secretion of LH.
C. Is produced by nurse cells in testes and inhibits the secretion of LH.
D. Inhibits the secretion of H, FSH and prolactin

Explanation

To identify the correct statement about 'inhibin', we will analyze the options provided and the functions of inhibin in the human reproductive system.

### Step-by-Step Solution:

1. **Understanding Inhibin**: Inhibin is a hormone that plays a crucial role in the regulation of reproductive hormones. It is primarily involved in the feedback mechanism that controls the secretion of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH).

2. **Identifying the Source**: Inhibin is produced by specific cells in the reproductive system:
- In females, it is produced by the **granulosa cells** of the ovaries.
- In males, it is produced by the **Sertoli cells** in the testes.

3. **Functions of Inhibin**: The primary function of inhibin is to inhibit the secretion of FSH and LH from the anterior pituitary gland. This is part of a feedback loop that helps regulate the production of gametes (sperm in males and eggs in females).

4. **Analyzing the Options**:
- **Option 1**: "Is produced by granulosa cells in ovary." - This is partially correct but does not mention its function.
- **Option 2**: "Is produced by granulosa cells in ovary and inhibits the secretion of LH." - This is correct as it states both the source and function.
- **Option 3**: "Is produced by nerve cells in testes and inhibits the secretion of LH." - This is incorrect because inhibin is not produced by nerve cells.
- **Option 4**: "Inhibits the secretion of LH, FSH and prolactin." - This is incorrect because inhibin primarily inhibits LH and FSH, but not prolactin.

5. **Conclusion**: The correct statement regarding inhibin is **Option 2**: "Is produced by granulosa cells in ovary and inhibits the secretion of LH."