Colchicine brings about :

Options

A. chromosome aberration
B. duplication of chromosomes
C. gene mutation
D. quick replication

Answer

**Step-by-Step Solution:**

1. **Understanding Colchicine**: Colchicine is an alkaloid, which is a type of secondary metabolite derived from the plant Colchicum. It has specific effects on cellular processes.

2. **Role of Microtubules in Cell Division**: During cell division, microtubules are crucial for the separation of duplicated chromosomes. They form the spindle apparatus that helps in pulling apart the chromosomes to opposite poles of the cell.

3. **Effect of Colchicine on Microtubules**: Colchicine prevents the polymerization of microtubules. This means that it stops the formation of microtubules necessary for the spindle apparatus during cell division.

4. **Consequences of Microtubule Inhibition**: When microtubules cannot form, the duplicated chromosomes cannot be separated during cell division. This leads to a situation where the chromosomes remain in the same cell, effectively causing a duplication of chromosomes.

5. **Conclusion**: Since colchicine inhibits the separation of chromosomes by affecting microtubules, it results in the duplication of chromosomes within the same cell. Therefore, the correct answer to the question is that colchicine brings about the duplication of chromosomes.

**Final Answer**: Colchicine brings about duplication of chromosomes.

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