Genetically engineered human insulin is synthesized with the help of

Options

A. rhizopus
B. rabbit/guinea pig
C. E. coli
D. Pseudomonas

Answer

**Step-by-Step Solution:**

1. **Understanding the Question:**
The question asks about the organism that helps in the synthesis of genetically engineered human insulin.

2. **Identifying the Options:**
The options provided are:
- Rhizopus
- Rabbit and guinea pig
- E. coli
- Pseudomonas

3. **Analyzing Each Option:**
- **Rhizopus:** This is a type of fungus, not typically used for insulin production.
- **Rabbit and Guinea Pig:** These are animals and not used for the synthesis of human insulin.
- **E. coli:** This is a bacterium commonly used in genetic engineering due to its ability to replicate plasmids.
- **Pseudomonas:** This is another type of bacterium but is not primarily used for insulin production.

4. **Choosing the Correct Answer:**
The correct answer is **E. coli**. This bacterium is used because it can be genetically modified to produce human insulin.

5. **Understanding the Process:**
- The process involves isolating the human insulin gene.
- This gene is then inserted into a plasmid (a small circular DNA molecule).
- The plasmid is introduced into E. coli.
- The E. coli bacteria multiply, and as they do, they replicate the plasmid containing the insulin gene.
- Finally, insulin is harvested from the culture.

6. **Conclusion:**
Therefore, genetically engineered human insulin is synthesized with the help of **E. coli**.

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