Cyclosporine-A: an immunosuppressive agent is produced by the fungus

Options

A. Fusarium graminearum
B. Trichoderma pollysporum
C. Aspergillus niger
D. Chaetomium cellulolyticum

Answer

**Step-by-Step Solution:**

1. **Understanding the Question**: The question asks which fungus produces Cyclosporine A, an immunosuppressive agent.

2. **Analyzing the Options**: We have four options to consider:
- A) Fusarium graminearum
- B) Trichoderma polysperum
- C) Aspergillus niger
- D) Cumulitium celluliticum

3. **Evaluating Each Option**:
- **Option A: Fusarium graminearum**: This fungus is known to be a plant pathogen that causes Fusarium head blight in wheat and barley. It is not associated with the production of Cyclosporine A.
- **Option B: Trichoderma polysperum**: This fungus is specifically noted for its role in the commercial production of Cyclosporine A, making it a strong candidate for the correct answer.
- **Option C: Aspergillus niger**: This fungus is primarily used for the production of citric acid and various enzymes, but it is not involved in the production of Cyclosporine A.
- **Option D: Cumulitium celluliticum**: This fungus is associated with the production of cellulase, an enzyme that breaks down cellulose, but it does not produce Cyclosporine A.

4. **Conclusion**: Based on the analysis, the only fungus that produces Cyclosporine A is **Trichoderma polysperum**. Therefore, the correct answer is **Option B**.

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