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alpha-and beta-Glucose differ in the ori...

`alpha-`and `beta-`Glucose differ in the orientation of the `(-OH)` group around:

A

`C_(3)`

B

`C_(1)`

C

`C_(5)`

D

`C_(2)`

Text Solution

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The correct Answer is:
To answer the question about how alpha and beta glucose differ in the orientation of the -OH group, we can follow these steps: ### Step-by-Step Solution: 1. **Understanding Anomers**: - Anomers are a type of stereoisomer that differ in configuration at the anomeric carbon (C1) when a sugar cyclizes. In the case of glucose, the anomeric carbon is the carbon that was part of the carbonyl group (C=O) in the straight-chain form of the sugar. 2. **Cyclic Structure of Glucose**: - Glucose can exist in a cyclic form, which is formed when the hydroxyl group (-OH) on C5 reacts with the carbonyl group (C1). This reaction leads to the formation of a hemiacetal. 3. **Identifying Alpha and Beta Forms**: - In the cyclic structure of glucose, the orientation of the -OH group on the anomeric carbon (C1) determines whether the glucose is in the alpha or beta form. - If the -OH group on C1 is positioned below the plane of the ring, it is referred to as alpha-glucose (α-glucose). - If the -OH group on C1 is positioned above the plane of the ring, it is referred to as beta-glucose (β-glucose). 4. **Conclusion**: - Therefore, alpha and beta glucose differ in the orientation of the -OH group around the C1 carbon atom. ### Final Answer: Alpha and beta glucose differ in the orientation of the -OH group around **C1**. ---
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