Enzyme that catalyse endergoinc synthesis coupled with exergonic hydrolysis of ATP are

Options

A. Ligases
B. Lyases
C. Hydrolases
D. Oxidoreductase

Answer

To answer the question regarding which enzymes catalyze endergonic synthesis coupled with exergonic hydrolysis of ATP, we can follow these steps:

### Step-by-Step Solution:

1. **Understand the Types of Reactions**:
- **Endergonic Reactions**: These are reactions that require energy input to proceed. They are non-spontaneous and have a positive change in free energy (ΔG > 0).
- **Exergonic Reactions**: These are reactions that release energy. They are spontaneous and have a negative change in free energy (ΔG < 0).

2. **Identify the Role of ATP**:
- ATP (adenosine triphosphate) is a molecule that stores and provides energy for various cellular processes. The hydrolysis of ATP (breaking down ATP into ADP and inorganic phosphate) releases energy, which can be harnessed to drive endergonic reactions.

3. **Know the Enzyme Classes**:
- Enzymes are classified into six main categories:
- **Oxidoreductases**: Catalyze oxidation-reduction reactions.
- **Transferases**: Catalyze the transfer of functional groups.
- **Hydrolases**: Catalyze hydrolysis reactions.
- **Lyases**: Catalyze the addition or removal of groups to form double bonds.
- **Isomerases**: Catalyze the rearrangement of molecules.
- **Ligases (or Synthetases)**: Catalyze the joining of two molecules with the use of ATP.

4. **Identify the Correct Enzyme Class**:
- The question specifically asks for enzymes that catalyze endergonic synthesis coupled with the exergonic hydrolysis of ATP. This function is characteristic of **Ligases** (or Synthetases), as they facilitate the synthesis of larger molecules from smaller ones, utilizing the energy released from ATP hydrolysis.

5. **Conclusion**:
- Therefore, the correct answer to the question is that the enzymes that catalyze endergonic synthesis coupled with exergonic hydrolysis of ATP are **Ligases**.

### Final Answer:
The enzyme that catalyzes endergonic synthesis coupled with exergonic hydrolysis of ATP is **Ligases**.

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