Excess of which of the following hormones causes Cushing's syndrome ?

Options

A. thyroxine
B. Adrenaline
C. Noradrenaline
D. Cortisol

Answer

To determine which hormone excess causes Cushing's syndrome, we can follow these steps:

### Step-by-Step Solution:

1. **Understand Cushing's Syndrome**:
- Cushing's syndrome is a condition characterized by excessive levels of cortisol in the blood. It can lead to various symptoms such as weight gain, high blood pressure, and changes in skin appearance.

2. **Review the Hormones Listed**:
- The options provided are:
- A. Thyroxin
- B. Adrenal
- C. Non-Adrenal
- D. Cortisol

3. **Analyze Each Option**:
- **Option A: Thyroxin**:
- Thyroxin is produced by the thyroid gland. Excess thyroxin leads to hyperthyroidism, not Cushing's syndrome.
- **Option B: Adrenal**:
- This term generally refers to hormones produced by the adrenal glands, but it is not specific. Excess adrenal hormones can affect heart rate and respiration but are not directly linked to Cushing's syndrome.
- **Option C: Non-Adrenal**:
- Similar to the adrenal option, this is vague and does not specify a particular hormone. It also does not relate to Cushing's syndrome.
- **Option D: Cortisol**:
- Cortisol is produced by the adrenal cortex. An excess of cortisol, often due to a tumor in the adrenal cortex, is the primary cause of Cushing's syndrome.

4. **Conclusion**:
- Based on the analysis, the hormone that causes Cushing's syndrome when present in excess is **Cortisol**.

### Final Answer:
- The excess of **Cortisol** causes Cushing's syndrome.

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