Obsteoporosis results from lesser calcium in bones. This may be due to

Options

A. hyperactivity of both adrenal cortex and parathyroid glands
B. hypoactivity of both adrenal cortex and parathyroid glands
C. hypoactivity of adrenal cortex and hyper activity of parathyroid gland
D. hperactivity of adrenal cortex and hypoactivity of parathyroid gland

Answer

### Step-by-Step Solution:

1. **Understanding Osteoporosis**: Osteoporosis is a condition characterized by weakened bones due to a decrease in bone mineral density, primarily caused by a deficiency of calcium in the bones.

2. **Identifying the Role of Glands**: The parathyroid glands play a crucial role in regulating calcium levels in the body by secreting parathyroid hormone (PTH). PTH increases blood calcium levels by releasing calcium from bones and enhancing calcium absorption in the intestines.

3. **Effects of Parathyroid Gland Activity**:
- **Hyperactivity of Parathyroid Gland**: If the parathyroid glands are hyperactive, they secrete excessive amounts of PTH. This leads to an increased release of calcium from bones, resulting in lower calcium content in the bones, which contributes to osteoporosis.
- **Hypoactivity of Parathyroid Gland**: Conversely, if the parathyroid glands are hypoactive, they would not secrete enough PTH, leading to insufficient calcium release from bones, which does not directly cause osteoporosis.

4. **Role of Adrenal Cortex**: The adrenal cortex secretes cortisol, which can also affect bone health.
- **Hyperactivity of Adrenal Cortex**: If the adrenal cortex is hyperactive, it produces excess cortisol. Cortisol can inhibit calcium absorption and decrease bone cell growth, leading to reduced bone density and potentially contributing to osteoporosis.
- **Hypoactivity of Adrenal Cortex**: If the adrenal cortex is hypoactive, it would not contribute to osteoporosis through cortisol effects.

5. **Evaluating Options**:
- The options provided include various combinations of gland activity.
- The correct answer is the combination where there is hyperactivity of the parathyroid gland and possibly hyperactivity of the adrenal cortex, as both conditions can lead to decreased calcium in bones.

6. **Conclusion**: The most likely cause of osteoporosis, based on the roles of these glands, is the hyperactivity of the parathyroid gland and potentially the adrenal cortex, leading to reduced calcium levels in bones.

### Final Answer:
Osteoporosis results from lesser calcium in bones, which may be due to the hyperactivity of the parathyroid gland and/or the hyperactivity of the adrenal cortex.

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