Condition of concentration of ketone body in urine is

Options

A. acromegaly
B. diabetes mellitus
C. turner's syndrome
D. sickle - cell anaemia

Answer

To determine the condition of concentration of ketone bodies in urine, we need to analyze the options provided: acromegaly, diabetes mellitus, Turner syndrome, and sickle cell anemia.

### Step-by-Step Solution:

1. **Understanding Ketone Bodies**:
- Ketone bodies are produced when the body breaks down fat for energy, particularly when glucose is not available. This often occurs in conditions where there is insufficient insulin or when the body cannot utilize glucose effectively.

2. **Analyzing Each Condition**:
- **Sickle Cell Anemia**:
- This is a genetic disorder affecting the shape of red blood cells. It primarily impacts oxygen transport and does not directly relate to ketone body production. Therefore, it is not associated with increased ketone bodies in urine.

- **Turner Syndrome**:
- This is a genetic disorder characterized by the presence of a single X chromosome. It does not have a direct link to ketone body production or concentration in urine, as it primarily affects sexual development and growth.

- **Diabetes Mellitus**:
- In diabetes mellitus, the body either does not produce enough insulin or the cells do not respond effectively to insulin. This leads to high blood sugar levels, but the cells cannot utilize glucose for energy. As a result, the body starts breaking down fats for energy, leading to the production of ketone bodies. These ketone bodies can accumulate in the blood and are subsequently excreted in the urine, leading to a condition known as ketonuria.

- **Acromegaly**:
- Acromegaly is caused by excess growth hormone, usually due to a pituitary tumor. While it can lead to various metabolic changes, it is not directly associated with the concentration of ketone bodies in urine.

3. **Conclusion**:
- Among the options provided, the condition that leads to the concentration of ketone bodies in urine is **Diabetes Mellitus**.

### Final Answer:
The condition of concentration of ketone bodies in urine is **Diabetes Mellitus**.

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