Which is inappropriate among the following in terms of the concept that `([A])/([T]) and ([G])/([C])` in DNA is equal to one?

Options

A. coliphage `phixx174`
B. polio virus
C. TMV
D. all of these

Answer

To solve the question regarding which option is inappropriate in terms of the concept that \([A]/[T]\) and \([G]/[C]\) in DNA is equal to one, we will analyze each option based on Chargaff's rules.

### Step-by-Step Solution:

1. **Understanding Chargaff's Rules**:
- Chargaff's rules state that in double-stranded DNA, the amount of adenine (A) is equal to thymine (T), and the amount of guanine (G) is equal to cytosine (C). This means that the ratios \([A]/[T] = 1\) and \([G]/[C] = 1\) hold true for double-stranded DNA.

2. **Identifying the Options**:
- The options given are:
- A) Coliphage 174
- B) Poliovirus
- C) TMV (Tobacco Mosaic Virus)
- D) All of these

3. **Analyzing Coliphage 174**:
- Coliphage 174 has single-stranded DNA as its genetic material. Chargaff's rules do not apply to single-stranded DNA, making this option inappropriate.

4. **Analyzing Poliovirus**:
- Poliovirus has RNA as its genetic material. Chargaff's rules are also not applicable to RNA, so this option is inappropriate as well.

5. **Analyzing TMV (Tobacco Mosaic Virus)**:
- TMV also has RNA as its genetic material. Similar to the poliovirus, Chargaff's rules do not apply here either.

6. **Conclusion**:
- Since Chargaff's rules do not apply to any of the options (Coliphage 174, Poliovirus, and TMV), the correct answer is D) All of these.

### Final Answer:
**D) All of these**