Best method to determine paternity is

Options

A. Protein analysis
B. chromosomes counting
C. gene counting
D. DNA finger printing

Answer

To determine the best method for establishing paternity, we can analyze the options provided: protein analysis, chromosome counting, genome counting, and DNA fingerprinting.

### Step-by-Step Solution:

1. **Understanding Paternity**: Paternity refers to the biological relationship between a father and his offspring. To determine paternity, we need to identify genetic material that is inherited from both parents.

2. **Reviewing the Options**:
- **Protein Analysis**: This method examines the proteins produced in an organism. While it can provide some information about genetic relationships, it is not specific enough to determine paternity accurately.
- **Chromosome Counting**: Humans have a fixed number of chromosomes (46). While chromosome counting can confirm if an individual is human, it does not provide specific information about paternity.
- **Genome Counting**: This term is less commonly used and generally refers to counting the total number of genes or the entirety of genetic material, which again does not directly establish paternity.
- **DNA Fingerprinting**: This method analyzes specific patterns in an individual's DNA. Each person has a unique DNA profile (except for identical twins), making it an effective tool for determining biological relationships.

3. **Conclusion**: Among the methods listed, DNA fingerprinting is the best method to determine paternity. It allows for the comparison of DNA samples from the child and potential father, revealing whether there is a biological connection.

### Final Answer:
The best method to determine paternity is **DNA fingerprinting**.

---