Where is the enzyme that catalyzes peptide bonding located?

Options

A. Larger sub-unit of the ribosome
B. smaller sub-unit of the ribosome
C. leader region of the m-RNA
D. t-RNA

Answer

To answer the question "Where is the enzyme that catalyzes peptide bonding located?", we can follow these steps:

### Step-by-Step Solution:

1. **Identify the Enzyme**: The enzyme responsible for catalyzing peptide bonds is called peptidyl transferase.

2. **Understand Peptide Bond Formation**: Peptidyl transferase facilitates the formation of peptide bonds between amino acids during protein synthesis. This process involves linking the carboxyl group of one amino acid to the amino group of another.

3. **Locate the Enzyme**: Peptidyl transferase activity is associated with the ribosome, which is the cellular machinery responsible for protein synthesis.

4. **Differentiate Ribosomal Subunits**: The ribosome is composed of two subunits: a larger subunit and a smaller subunit. The peptidyl transferase activity is specifically an integral part of the larger subunit of the ribosome.

5. **Select the Correct Option**: Given the options:
- Option 1: Largest subunit of ribosome
- Option 2: Smaller subunit of ribosome
- Option 3: Leader region of mRNA
- Option 4: tRNA

The correct answer is **Option 1: Largest subunit of ribosome**.

### Final Answer:
The enzyme that catalyzes peptide bonding, known as peptidyl transferase, is located in the largest subunit of the ribosome.

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