Go through the following statements
(i) 2'-OH group present at every nucleotide in RNA makes RNA labile and easily degradable.
(ii) The transcription and translation can be coupled in bacteria
(iii) the promoter is located towards the 5'-end while terminator is located towards the 3'end of the template strand.
(iv). In lac operon, the z gene codes for beta galactosidase, y gene codes for permease while i gene codes for the inducer.
Which of these are correct statement:

Options

A. (ii),(iiii) & (iv)
B. (i) & (ii)
C. (i),(ii) & (iii)
D. All are correct

Explanation

To determine which statements are correct, let's analyze each statement step by step:

### Step 1: Analyze Statement (i)
**Statement:** 2'-OH group present at every nucleotide in RNA makes RNA labile and easily degradable.

**Explanation:**
The presence of the 2'-OH group in RNA nucleotides makes RNA more reactive and susceptible to hydrolysis compared to DNA, which lacks this group. This characteristic indeed makes RNA less stable and more easily degradable.

**Conclusion:** This statement is **correct**.

### Step 2: Analyze Statement (ii)
**Statement:** The transcription and translation can be coupled in bacteria.

**Explanation:**
In prokaryotes, such as bacteria, transcription (the synthesis of RNA from DNA) and translation (the synthesis of proteins from RNA) can occur simultaneously. This is because there is no nuclear membrane to separate the processes, allowing ribosomes to attach to the mRNA while it is still being synthesized.

**Conclusion:** This statement is **correct**.

### Step 3: Analyze Statement (iii)
**Statement:** The promoter is located towards the 5'-end while terminator is located towards the 3'-end of the template strand.

**Explanation:**
The promoter region is indeed located at the 5' end of the coding strand (not the template strand). The terminator is located at the 3' end of the coding strand as well. The statement incorrectly refers to the template strand instead of the coding strand.

**Conclusion:** This statement is **incorrect**.

### Step 4: Analyze Statement (iv)
**Statement:** In lac operon, the z gene codes for beta galactosidase, y gene codes for permease while i gene codes for the inducer.

**Explanation:**
In the lac operon, the z gene does code for beta-galactosidase, and the y gene codes for permease. However, the i gene codes for the repressor protein, not the inducer. The inducer in the lac operon is allolactose, which binds to the repressor.

**Conclusion:** This statement is **incorrect**.

### Final Conclusion:
The correct statements are:
- (i) 2'-OH group present at every nucleotide in RNA makes RNA labile and easily degradable.
- (ii) The transcription and translation can be coupled in bacteria.

Thus, the correct answer is **(i) and (ii)**.

---