Automated - DNA sequencers are based on method developed by

Options

A. Erwin chargaff
B. Maurice wilkins
C. Frederick sanger
D. Francis crick

Answer

**Step-by-Step Solution:**

1. **Understand the Question**: The question asks about the scientist who developed the method on which automated DNA sequencers are based.

2. **Contextual Background**: Automated DNA sequencers are crucial tools in genetics, particularly in projects like the Human Genome Project. They help determine the sequence of nucleotides in DNA.

3. **Evaluate the Options**:
- **Option A: Erwin Chargaff**: He is known for Chargaff's rules, which describe the base pairing in DNA (A=T and G=C). His work does not relate to DNA sequencing methods.
- **Option B: Morris Wilkins**: He contributed to the discovery of the DNA structure through X-ray diffraction techniques, but he did not develop a method for DNA sequencing.
- **Option C: Frederick Sanger**: He developed the Sanger sequencing method, which is the basis for automated DNA sequencing. This method allows for the determination of the nucleotide sequence of DNA.
- **Option D: Francis Crick**: He, along with James Watson, is known for elucidating the structure of DNA and the central dogma of molecular biology, but he did not develop a sequencing method.

4. **Identify the Correct Answer**: Based on the evaluations, the correct answer is **Frederick Sanger** (Option C), as he developed the method that automated DNA sequencers utilize.

5. **Conclusion**: The automated DNA sequencers are based on the method developed by Frederick Sanger.

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