Which one of the following is a wrong statement regarding mutations

Options

A. UV and gamma rays are mutagens
B. Change in a single base pair of DNA does not cause mutation
C. Deletion and insertion of base pairs cause frame-shift mutation
D. cancer cells commonly show chromosomal aberrations

Answer

To determine which statement regarding mutations is incorrect, we will analyze each option provided in the question.

### Step-by-Step Solution:

1. **Understanding Mutations**:
- A mutation is defined as any change in the DNA sequence. This can include changes in a single base pair, multiple base pairs, or larger segments of DNA.

2. **Analyzing the Options**:
- **Option 1**: "UV and gamma rays are mutagens."
- This statement is **correct**. Both UV and gamma rays are known to cause mutations by damaging the DNA.

- **Option 2**: "Change in a single base pair of DNA does not cause mutation."
- This statement is **incorrect**. A change in a single base pair is indeed a mutation and is specifically referred to as a point mutation. Therefore, this is the wrong statement regarding mutations.

- **Option 3**: "Deletion and insertion of base pairs cause frameshift mutation."
- This statement is **correct**. When base pairs are deleted or inserted, it shifts the reading frame of the genetic code, leading to frameshift mutations.

- **Option 4**: "Cancer cells show chromosomal aberrations."
- This statement is **correct**. Cancer cells often exhibit chromosomal abnormalities, which can include changes in the number or structure of chromosomes.

3. **Conclusion**:
- The only incorrect statement regarding mutations is: "Change in a single base pair of DNA does not cause mutation."

### Final Answer:
The wrong statement regarding mutations is: "Change in a single base pair of DNA does not cause mutation."

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