Phosphorylation of glucose during glycolysis is catalysed by

Options

A. Phosphoglucomutase
B. Phlosphoglucoisomerase
C. Hexokinase
D. Phosphorylase

Answer

To answer the question regarding which enzyme catalyzes the phosphorylation of glucose during glycolysis, we can follow these steps:

### Step-by-Step Solution:

1. **Understanding Glycolysis**: Glycolysis is a metabolic pathway that breaks down glucose into pyruvate, producing energy in the form of ATP. It consists of several steps, each catalyzed by specific enzymes.

2. **Identifying Phosphorylation**: Phosphorylation refers to the addition of a phosphate group to a molecule. In the context of glycolysis, the first step involves the phosphorylation of glucose.

3. **First Step of Glycolysis**: In the first step of glycolysis, glucose is converted into glucose 6-phosphate. This reaction involves the addition of a phosphate group to glucose.

4. **Role of ATP**: The phosphorylation process requires energy, which is provided by ATP. In this reaction, ATP is converted into ADP (adenosine diphosphate) as it donates a phosphate group.

5. **Identifying the Enzyme**: The enzyme responsible for catalyzing the phosphorylation of glucose to glucose 6-phosphate is known as **hexokinase**. Hexokinase facilitates the transfer of the phosphate group from ATP to glucose.

6. **Conclusion**: Therefore, the correct answer to the question is that the phosphorylation of glucose during glycolysis is catalyzed by **hexokinase**.