`CO_(2)` dissocated from carbamino haemoglobin when

Options

A. `pCO_2` is high `pO_2` is low
B. `pCO_2` is high and `pCO_2` is low
C. `pO_2` is high and `pCO_2` is low
D. None of the above

Answer

To solve the question regarding the dissociation of CO₂ from carbamino hemoglobin, we can follow these steps:

### Step-by-Step Solution:

1. **Understanding Carbamino Hemoglobin**:
- Carbamino hemoglobin is formed when carbon dioxide (CO₂) binds to hemoglobin. This occurs primarily in the tissues where CO₂ concentration is high.

2. **Role of Partial Pressure**:
- The dissociation of CO₂ from carbamino hemoglobin is influenced by the partial pressures of CO₂ and oxygen (O₂).

3. **Haldane Effect**:
- The Haldane effect describes how the binding of oxygen to hemoglobin reduces its affinity for CO₂. When O₂ levels are high, hemoglobin tends to release CO₂ more readily.

4. **Conditions in the Lungs**:
- In the lungs, the partial pressure of oxygen is high due to inhalation, while the partial pressure of carbon dioxide is low because CO₂ is being exhaled.

5. **Conclusion**:
- Therefore, when the partial pressure of oxygen is high and the partial pressure of carbon dioxide is low, CO₂ dissociates from carbamino hemoglobin. This is the condition that favors the unloading of CO₂ in the lungs.

6. **Final Answer**:
- The correct option is: **Partial pressure of oxygen is high and partial pressure of carbon dioxide is low**.