The oxygen - haemoglobin dissociation curve will show a right shift in case of

Options

A. High `pCO_2`
B. High `pCO_2`
C. Low `pCO_2`
D. Less `H^+` concentration

Answer

To solve the question regarding the oxygen-hemoglobin dissociation curve and its right shift, we can follow these steps:

### Step-by-Step Solution:

1. **Understanding the Oxygen-Hemoglobin Dissociation Curve**:
- The oxygen-hemoglobin dissociation curve illustrates how readily hemoglobin binds to oxygen at various partial pressures of oxygen (pO2). It typically has a sigmoid shape.

2. **Identifying Factors Affecting the Curve**:
- The position of the curve can shift to the right or left based on several physiological factors, including:
- pH levels (acidity or alkalinity)
- Temperature
- Partial pressure of carbon dioxide (pCO2)
- Concentration of 2,3-bisphosphoglycerate (2,3-BPG)

3. **Right Shift of the Curve**:
- A right shift in the curve indicates that hemoglobin has a decreased affinity for oxygen, meaning it releases oxygen more readily to the tissues. This shift can occur under certain conditions:
- Increased levels of carbon dioxide (high pCO2)
- Decreased pH (more acidic conditions)
- Increased temperature

4. **Analyzing the Given Options**:
- The question provides options regarding the conditions under which the curve will shift to the right:
- High partial pressure of carbon dioxide
- Low partial pressure of carbon dioxide
- Least hydrogen concentration

5. **Selecting the Correct Answer**:
- Out of the given options, the correct answer is **high partial pressure of carbon dioxide**. This condition leads to a right shift in the oxygen-hemoglobin dissociation curve, promoting oxygen release to tissues.

### Final Answer:
The oxygen-hemoglobin dissociation curve will show a right shift in case of **high partial pressure of carbon dioxide**.

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