Select the option which is not correct with respect to enzyme action

Options

A. Malonate is a competitive inhibitor of succinic dehydrogenase
B. Substrate binds with enzyme at its active site
C. Addition of lot of succinate does not reverse the inhibition of succinic dehydro- genase by malonate
D. A non-competitive inhibitor binds the enzyme at a site distinct from that which binds the substrate

Explanation

To solve the question regarding enzyme action and identify the incorrect statement, we will analyze each option step by step.

### Step-by-Step Solution:

1. **Understanding Competitive Inhibition**:
- The first statement claims that malonate is a competitive inhibitor of succinic dehydrogenase (SDH).
- In competitive inhibition, the inhibitor (malonate) competes with the substrate (succinate) for binding to the active site of the enzyme.
- Since malonate can bind to the active site of SDH, this statement is **true**.
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