The first artificial cloning vector was

Options

A. pBR322
B. M13
C. phagemid vectors
D. cosmid Vectors

Answer

**Step-by-Step Solution:**

1. **Understanding Cloning Vectors:**
Cloning vectors are essential tools in genetic engineering. They are used to carry and replicate desired recombinant DNA within a host cell.

2. **Identifying the Options:**
The question provides four options:
- A) PBR 322
- B) M13
- C) Fezmit vectors
- D) Cosmit vectors

3. **Evaluating Each Option:**
- **Option A: PBR 322**
- PBR 322 is recognized as the first artificial cloning vector. It was constructed to facilitate the cloning of DNA.
- **Option B: M13**
- M13 is a filamentous bacteriophage and not classified as a cloning vector. It is primarily used in molecular biology but does not fit the definition of an artificial cloning vector.
- **Option C: Fezmit vectors**
- This term does not correspond to a known category of cloning vectors in genetic engineering.
- **Option D: Cosmit vectors**
- Cosmid vectors are hybrids between plasmids and phage vectors, but they are not the first artificial cloning vector.

4. **Conclusion:**
After evaluating all options, it is clear that the first artificial cloning vector is **PBR 322**.

**Final Answer:**
The first artificial cloning vector was **PBR 322**.

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