At which stage of meiosis, recombinant DNA is made?

Options

A. Zygotene
B. Diplotene
C. Metaphase-I
D. Pachytene

Answer

To answer the question "At which stage of meiosis is recombinant DNA made?", we can break down the solution into the following steps:

### Step-by-Step Solution:

1. **Understanding Meiosis**:
- Meiosis is a type of cell division that reduces the chromosome number by half, resulting in four haploid daughter cells from one diploid germ cell. It consists of two main stages: Meiosis I and Meiosis II.

2. **Stages of Meiosis**:
- Meiosis I includes several phases: Prophase I, Metaphase I, Anaphase I, and Telophase I. Prophase I is further divided into sub-stages: Leptotene, Zygotene, Pachytene, Diplotene, and Diakinesis.

3. **Identifying the Relevant Stage**:
- The question specifically asks about the formation of recombinant DNA. This occurs during Prophase I of Meiosis I.

4. **Focus on Pachytene**:
- Within Prophase I, the Pachytene stage is crucial because it is during this phase that crossing over occurs. Crossing over involves the exchange of genetic material between non-sister chromatids of homologous chromosomes.

5. **Formation of Recombinant DNA**:
- Due to crossing over in the Pachytene stage, new combinations of alleles are formed, resulting in recombinant DNA.

6. **Conclusion**:
- Therefore, the correct answer to the question is that recombinant DNA is made during the **Pachytene** stage of Meiosis I.

### Final Answer:
Recombinant DNA is made during the **Pachytene** stage of meiosis.

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