How can a structural alteration of a chromosome be detected by looking at the chromosome through a microsope?

Explanation

To detect a structural alteration of a chromosome through a microscope, the following steps can be taken:

### Step-by-Step Solution:

1. **Sample Collection**: Obtain a sample of cells from the patient. This can be done through various methods such as blood draw, bone marrow aspiration, or tissue biopsy.

2. **Cell Culture**: Allow the collected cells to grow and divide in a laboratory setting. This is necessary to increase the number of cells available for analysis.

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