Which of the following cells release pepsinogen in stomach?

Options

A. chief cells
B. oxyntic cells
C. goblet cells
D. parietal cells

Explanation

To determine which cells release pepsinogen in the stomach, let's analyze the options provided:

1. **Identify the cells involved in gastric secretion**: The stomach contains several types of cells that play different roles in digestion. The main types of cells include:
- Chief cells
- Parietal cells (also known as oxyntic cells)
- Goblet cells

2. **Understand the function of each cell type**:
- **Chief cells**: These cells are responsible for secreting pepsinogen, which is an inactive precursor of the enzyme pepsin. Pepsinogen is converted to pepsin in the presence of hydrochloric acid (HCl) secreted by parietal cells.
- **Parietal cells (or oxyntic cells)**: These cells secrete hydrochloric acid (HCl) and intrinsic factor, which is important for vitamin B12 absorption. They do not secrete pepsinogen.
- **Goblet cells**: These cells secrete mucus, which protects the stomach lining from the corrosive effects of HCl. They do not secrete pepsinogen.

3. **Conclusion**: Since the question specifically asks for the cells that release pepsinogen, the correct answer is **chief cells**.

Thus, the final answer is:
**Chief cells release pepsinogen in the stomach.**