Duodenum has characteristic Brunner's glands which secrete two hormones called

Options

A. prolactin, parathormone
B. estradiol, progesterone
C. kinase, estrogens
D. secretin, cholecystokinin

Explanation

**Step-by-Step Solution:**

1. **Identify the Glands**: The question refers to the Brunner's glands, which are also known as duodenal glands. These glands are located in the submucosa of the duodenum.

2. **Understand the Function**: Brunner's glands play a crucial role in the digestive process. They secrete substances that help in the digestion and neutralization of stomach acid.

3. **Identify the Hormones**: The two primary hormones secreted by the Brunner's glands are:
- **Secretin**
- **Cholecystokinin (CCK)**

4. **Function of Secretin**: Secretin is released in response to acidic chyme entering the duodenum. Its main function is to stimulate the pancreas and bile duct to release sodium bicarbonate, which helps neutralize the acidity of the chyme.

5. **Function of Cholecystokinin**: Cholecystokinin is secreted in response to partially digested fats and proteins. It stimulates the pancreas to release digestive enzymes and causes the gallbladder to contract, releasing bile into the duodenum.

6. **Conclusion**: Therefore, the two hormones secreted by the Brunner's glands in the duodenum are secretin and cholecystokinin.

**Final Answer**: The two hormones secreted by Brunner's glands in the duodenum are **secretin** and **cholecystokinin**.

---