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What is the role of RNA-mediated interfe...

What is the role of RNA-mediated interference?

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RNA-mediated interference (RNAi) is a technique by which the activity of a specific gene in crop plants is inhibited by introducing a gene that produces both sense and antisense strands of mRNA. These two strands pair to form a double-stranded RNA (dsRNA). It breaks into small fragments, called short interference RNAs (siRNAs). siRNA molecules bind to protein forming RNA Induced Silencing Complex (RISC). RISC cleave mRNA having complementary base sequence and makes the related gene silent. This method is used to silence the genes of microbes or other parasites that enter the eukaryotic hosts.
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