Who was the first patient who was given gene therapy? Why was the given treatment recurrent in nature?

Explanation

**Step-by-Step Solution:**

1. **Identify the First Patient of Gene Therapy**: The first patient to receive gene therapy was a 4-year-old girl named Ashanti DeSilva. She was diagnosed with a genetic disorder known as adenosine deaminase deficiency (ADA deficiency).

2. **Understand the Condition**: Adenosine deaminase deficiency is a genetic disorder that affects the immune system. It is caused by a deletion or mutation in the gene responsible for producing the enzyme adenosine deaminase, which is crucial for the breakdown of toxic metabolites in the body.

3. **Treatment Method**: The initial treatment for Ashanti involved gene therapy, which aimed to deliver a normal copy of the gene to replace the defective one. This was done through the introduction of genetically engineered lymphocytes (a type of white blood cell).

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