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ELISA technique is based on the principl...

ELISA technique is based on the principles of antigen-antibody interaction. Can this technique be used in the molecular diagnosis of a genetic disorder, such as phenylketonuria?

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Some genetic disorders like phenylketonuria can be diagnosed by ELISA technique using antibody against the enzyme phenylalanine hydroxylase, responsible for the metabolism of phenylalanine. A normal person having this enzyme gives positive result and a phenylketonuric person gives negative result with ELISA due to absence of enzyme.
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