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Change of active site, which prevents th...

Change of active site, which prevents the binding of substrate to enzyme and stops the reaction, is called :

A

reverse inhibition

B

competitive inhibition

C

allosteric inhibition

D

non-competitive inhibition

Text Solution

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The correct Answer is:
To solve the question regarding the change of the active site that prevents the binding of substrate to an enzyme and stops the reaction, we can follow these steps: ### Step-by-Step Solution: 1. **Understand the Question**: The question asks about a specific type of inhibition that alters the active site of an enzyme, preventing substrate binding and halting the reaction. 2. **Identify the Options**: The options provided are: - Reverse inhibition - Competitive inhibition - Allosteric inhibition - Non-competitive inhibition 3. **Analyze Each Option**: - **Reverse Inhibition**: This involves a temporary binding to the active site, which does not permanently change the active site. When the inhibitor is removed, the enzyme can function normally again. This does not fit the description. - **Competitive Inhibition**: In this case, an inhibitor competes with the substrate for binding at the active site. While it prevents substrate binding, it does not change the active site itself. Thus, this option is not correct. - **Allosteric Inhibition**: This occurs when an inhibitor binds to a site other than the active site, causing a conformational change in the enzyme. This change alters the active site, preventing substrate binding and stopping the reaction. This option fits the description given in the question. - **Non-competitive Inhibition**: Here, the inhibitor binds to a site other than the active site, which can change the enzyme's shape but does not necessarily alter the active site in a way that prevents substrate binding. This option is also not correct. 4. **Conclusion**: Based on the analysis, the correct answer is **Allosteric Inhibition**, as it is the type of inhibition that leads to a change in the active site, preventing substrate binding and stopping the reaction. ### Final Answer: **Allosteric Inhibition**
To solve the question regarding the change of the active site that prevents the binding of substrate to an enzyme and stops the reaction, we can follow these steps: ### Step-by-Step Solution: 1. **Understand the Question**: The question asks about a specific type of inhibition that alters the active site of an enzyme, preventing substrate binding and halting the reaction. 2. **Identify the Options**: The options provided are: - Reverse inhibition ...
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