Define the following :
Myxedema

Explanation

**Step-by-Step Text Solution:**

1. **Definition of Myxedema**: Myxedema is a medical term that refers to a severe form of hypothyroidism. It is characterized by a range of symptoms resulting from an underactive thyroid gland.

2. **Dermatological Changes**: Myxedema is often associated with specific dermatological changes in the skin. These changes can include swelling, thickening, and a waxy appearance of the skin, particularly in the face and extremities.

3. **Causes**: Myxedema typically results from undiagnosed or untreated severe hypothyroidism. It can also occur in individuals who have stopped taking their thyroid medication.

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