Persons suffering from sickle cell anaemia are at an advantage in Malaria infected areas.

Explanation

### Step-by-Step Solution:

1. **Understanding Sickle Cell Anemia**:
- Sickle cell anemia is an autosomal recessive genetic disorder caused by a mutation in the hemoglobin gene. This mutation leads to the production of abnormal hemoglobin known as hemoglobin S (HbS).

2. **Genetic Mutation**:
- The mutation occurs due to a point mutation in the DNA sequence. The normal codon GAG (which codes for glutamic acid) is replaced by the codon GUG (which codes for valine) at the sixth position of the beta-globin chain of hemoglobin.

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