In which direction is the new strand of DNA synthesised during replication?

Explanation

**Step-by-Step Solution:**

1. **Understanding DNA Replication**: DNA replication involves the synthesis of a new strand of DNA using an existing strand as a template. The enzyme responsible for this process is DNA-dependent DNA polymerase.

2. **Direction of Synthesis**: The key property of DNA polymerase is its polarity. It can only synthesize new DNA strands in the 5' to 3' direction. This means that the enzyme adds nucleotides to the 3' end of the growing strand.

3. **Template Strand Orientation**: During replication, the template strand can be oriented in two ways:
- The leading strand, which is synthesized continuously, runs in the 3' to 5' direction.
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