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Assertion: Temin modified Crick's 'centr...

Assertion: Temin modified Crick's 'central dogma' to 'central dogma reverse'.
Reason: Crick was of the view that flow of genetic information in cells is bidirectional.

A

If both Assertion and Reason are true and the Reason is the correct explanation of the Assertion.

B

If both Assertion and Reason are true and the Reason is not the correct explanation of the Assertion.

C

If Assertion is true but the Reason is false.

D

If both Assertion and Reasom are false.

Text Solution

AI Generated Solution

The correct Answer is:
To solve the assertion-reason question, we will analyze both the assertion and the reason statements step by step. ### Step 1: Understand the Assertion - **Assertion**: Temin modified Crick's 'central dogma' to 'central dogma reverse'. - **Explanation**: The central dogma of molecular biology, originally proposed by Francis Crick, describes the flow of genetic information from DNA to RNA to protein. Howard Temin, along with David Baltimore, proposed a modification to this concept when they discovered reverse transcription in retroviruses. This process involves the conversion of RNA back into DNA, which is contrary to the original unidirectional flow described by Crick. ### Step 2: Understand the Reason - **Reason**: Crick was of the view that the flow of genetic information in cells is bidirectional. - **Explanation**: This statement is incorrect. Crick's original concept of the central dogma was that the flow of genetic information is unidirectional: from DNA to RNA (transcription) and then from RNA to protein (translation). He did not propose that the flow of genetic information is bidirectional. ### Step 3: Evaluate the Statements - The assertion is true because Temin did indeed modify Crick's central dogma to include reverse transcription. - The reason is false because Crick did not believe in a bidirectional flow of genetic information; he proposed a unidirectional flow. ### Conclusion - The correct evaluation of the assertion and reason is that the assertion is true, but the reason is false. Therefore, the answer to the question is that the assertion is true and the reason is false. ### Final Answer - **Assertion**: True - **Reason**: False
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